Session date: May 23, 2023
Despite very early assumptions, children are not spared from COVID-19. However, biological and clinical responses vary considerably across the age spectrum. In this session, we will assess biologic responses to SARS-CoV-2, which will serve as a foundation for comparisons with other common respiratory viruses. We will discuss the passive transfer of maternal antibodies to infants and their clinical protection; airway signals in the upper airway in response to infection in children as compared to adults; hematologic biomarkers of severe infection in children and adults infected with SARS-CoV-2; and clinical and molecular findings in long COVID-19.
Despite very early assumptions, children are not spared from COVID-19. However, biological and clinical responses vary considerably across the age spectrum. In this session, we will assess biologic responses to SARS-CoV-2, which will serve as a foundation for comparisons with other common respiratory viruses. We will discuss the passive transfer of maternal antibodies to infants and their clinical protection; airway signals in the upper airway in response to infection in children as compared to adults; hematologic biomarkers of severe infection in children and adults infected with SARS-CoV-2; and clinical and molecular findings in long COVID-19.
• Better understand the role and durability of passive immunity against COVID-19 and other infections in newborns
• Understand immune responses in the airway in in circulation in response to acute SARS-CoV-2 infection
• Ascertain the clinical phenotype of long COVID-19 in kids and adults and review the latest research on pathogenicity
Andrea Edlow, MD, MSc
Marcus Mall, MD
Sharon Mcgrath-Morrow, MD
Lael Yonker, MD
Passive Immunity in Neonates
Airway Responses to SARS-CoV-2
Long COVID-19
Tying it Together