Bronchopulmonary dysplasia (BPD), the chronic lung disease of infancy, is the most common morbidity of preterm birth. Despite improvements in the respiratory care of infants born preterm, the incidence of BPD is increasing, owing to the improved survival of infants born extremely preterm. As increasing numbers of preterm infants survive to adulthood, BPD is increasingly recognized as an important contributor to morbidity and mortality throughout life even into adulthood. This session will situate current information regarding the molecular mechanisms of BPD pathogenesis within the context of longitudinal state-of-the-art, evidence-based respiratory care practices and outcomes research of individuals with established BPD.
• Describe new findings about pre- and postnatal molecular mechanisms of lung injury that may plausibly serve as therapeutic targets that mitigate severe respiratory disease trajectories in preterm at risk for BPD
• Integrate new guidelines into current practice related to the multidisciplinary care of children with established BPD with focus on: multidisciplinary BPD care programs, pulmonary vascular disease, and the application of advanced imaging
• Improve the quality of life/health status of patients with BPD by understanding how longitudinal pulmonary function trajectories in childhood, adolescence, and adulthood are modified by BPD
Matthew Kielt, MD
Steven Abman, MD
Erin Plosa, MD
Leif Nelin, MD
Shazia Bhombal, MD
Nara Higano, PhD
Sharon Mcgrath-Morrow, MD
Jennifer Wambach, MD, MS
Introduction
Antenatal Determinants of Bronchopulmonary Dysplasia
Lung Injury and Lung Developmental Programming in BPD
Multidisciplinary BPD Care
Evaluation and Management of Pulmonary Vascular Disease in BPD
Advanced Imaging in Bronchopulmonary Dysplasia
BPD Respiratory Trajectories in Childhood, Adolescence, and Adulthood
Panel Discussion