The association of metabolic dysregulation and obesity with lung disease has been brought to the forefront by the higher morbidity of COVID-19 in obese patients. By reviewing the literature on the epidemiology, mechanisms, and therapeutic options for pulmonary disease associated with metabolic dysregulation with/without obesity, this session will update Physicians and basic and translational science researchers on the burden and mechanisms of lung disease in adults and children with metabolic abnormalities. By highlighting similarities and differences between children and adults on the contribution of metabolic dysregulation on lung disease, the symposium will form the framework for a life-course approach on management of lung disease associated with metabolic dysregulation.
CME credits and/or Certificates of Completion are not provided for this session.
1- Recognize the high prevalence and contribution of metabolic abnormalities to pulmonary disease burden in children and adults
2- Understand the potential mechanisms elucidated to date underlying the association of metabolic abnormalities with lung disease
3- Learn the effective and not effective therapeutic interventions for lung disease associated with metabolic abnormalities
Fernando Holguin, MD, MPH: Metabolic Syndrome as a Risk Factor for Pulmonary Disease Incidence and Severity in Adults
Erick Forno, MD, MPH, ATSF: Metabolic Dysregulation and Childhood Lung Disease: Are Children Small Adults?
Anne E. Dixon, MD, BM CH, ATSF: Pathogenesis of Airway Disease Among Adults With Metabolic Dysregulation
Deepa Rastogi, MBBS, MS, ATSF: Metabolic Dysregulation, Inflammation and Lung Disease in Children
Anurag Agrawal, MD, PhD, ATSF: Role of Mitochondria in Metabolic Disease and Airway Disease Among Individuals With Normal BMI
Lisa G. Wood, PhD: Strategies Targeting Metabolic Syndrome in Children
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