This session will focus on the interplay between OSA-associated inflammation and chronic comorbidities. The session will begin by detailing both epidemiologic and genetic associations between OSA and inflammatory biomarkers, which are key mediators in the downstream cardiopulmonary consequences in OSA. Particular focus will be given to the contribution of OSA-associated inflammation in the acceleration of chronic comorbid diseases, including asthma, interstitial lung disease, cardiovascular disease, and HIV. The session will conclude with a discussion/Q&A that will explore future research areas for this important field.
• Describe the interplay of both biologic (genetic) and epidemiologic associations between OSA, chronic systemic inflammation and comorbid disease.this will improve medical knowledge and practice-based learning and improvement
• Understand the contribution of OSA in chronic comorbid diseases, including asthma, interstitial lung disease, cardiovascular disease, and HIV. This will improve medical knowledge, practice-based learning and improvement, and evidence-based practice
• Identify research goals for precision health and personalized medicine in patients with OSA and co-morbid chronic inflammatory disease. This will improve medical knowledge
Vaishnavi Kundel, MD
Sanja Jelic, MD
Rene Cortese, PhD
Brian Cade, PhD
Priya Borker, MD
Mihaela Teodorescu, MD, MS
Welcome and Introduction of Speakers
Sleep Apnea, Biomarkers of Vascular Injury and Inflammation
Role of Epigenetic Regulation in Sleep Apnea
Epidemiological and Genetic Associations Between Sleep-Disordered Breathing and Inflammatory Traits
Investigating the Impact of Sleep Health on HIV-Associated Inflammation
OSA and Chronic Lung Disease