Session date: May 24, 2023
Heterogeneity is increasingly recognized as a central challenge in critical care research. Sub-phenotyping and endotyping efforts designed to reduce heterogeneity in clinical trial populations and individualize treatment protocols are central to efforts to improve outcomes. In this session we discuss both established and novel techniques for phenotyping critically ill patients with the aim of familiarizing clinicians, clinical researchers and basic researchers with the latest in the field.
Heterogeneity is increasingly recognized as a central challenge in critical care research. Sub-phenotyping and endotyping efforts designed to reduce heterogeneity in clinical trial populations and individualize treatment protocols are central to efforts to improve outcomes. In this session we discuss both established and novel techniques for phenotyping critically ill patients with the aim of familiarizing clinicians, clinical researchers and basic researchers with the latest in the field.
- Describe novel approaches to phenotyping in acute critical care syndromes
Describe new findings concerning the complexity of critical care syndromes
Define new strategies to manage the care of ARDS and septic shock
Charles Hardin, MD, PhD, ATSF
Tiffanie Jones, MD, MPH, MSCE
Lisa Bastarache, MS
Pratik Sinha, MB BCh, PhD
Matthew Churpek, MD, MPH, PhD, ATSF
Untangling Complexity in Critical Illness
It’s Written in the Genes: Understanding the Susceptibilities to Critical Illness
Polygenic Risk Scores in Critical Care: A Tale of Two Post-Operative Complications
Phenotypes Over Clinical Syndromes: A More Logical Lumping Paradigm
Clinical Trials and Treatment Effects: Don’t be Average, Be an Individual