Session date: May 22, 2023
Mucus dysfunction plays a significant role in COPD, asthma, and cystic fibrosis. It has been stimulating progress in understanding the pathogenesis and imaging of mucus dysfunction. This progress includes the role of mucus mucins in disease pathogenesis and the use of imaging modalities, such as computed tomography, to evaluate this process. This significant progress has been combined with developing targeted therapeutics for mucus dysfunction in cystic fibrosis, furthering studies for therapies for other airway diseases. This session will present the advances in mucus dysfunction from pathogenesis and imaging to therapy.
Mucus dysfunction plays a significant role in COPD, asthma, and cystic fibrosis. It has been stimulating progress in understanding the pathogenesis and imaging of mucus dysfunction. This progress includes the role of mucus mucins in disease pathogenesis and the use of imaging modalities, such as computed tomography, to evaluate this process. This significant progress has been combined with developing targeted therapeutics for mucus dysfunction in cystic fibrosis, furthering studies for therapies for other airway diseases. This session will present the advances in mucus dysfunction from pathogenesis and imaging to therapy.
• Describe new findings on the pathogenesis of mucus dysfunction
• Recognize imaging features of mucus dysfunction readily to be applicable
• Describe the new therapies targeting mucus dysfunction
Joanna Conroy, MSc
Richard Boucher, MD
Susan Birket, PharmD, PhD
Eleanor Dunican, BM BCH
Alejandro Diaz, MD
Raksha Jain, MD, MSci, ATSF
Patient's Perspective
Mucus, Mucins, and Mucociliary Dysfunction: A Sticky Problem
Mucus Dysfunction in Cystic Fibrosis
Seeing Is Believing: Imaging of Mucus Plugs in Asthma and COPD 1
Seeing Is Believing: Imaging of Mucus Plugs in Asthma and COPD 2
The Dawn of a New Era: Therapies Targeting Mucus